Normally I access and read a dozen articles a week, all of them in PDF. I used to save them on my hard disk, by using a predefined naming system for the folders and articles.
Then I tried Mendeley for some while but I found it a little slow and heavy. Two days ago, I performed a small research on how to organize my personal library of science and then I found out Papers, from Mekentosj.
In a simple way, it’s just the software I’ve been looking at: organizes all the papers I have at my computer, renames them, saves them at a specific folder, matches the PDF with PubMed (merging all the info from the database), and much more.
If you think you could need something like this, just give it a try.
YouTube video from iKutticom “It’s like iTunes for your papers”
Astu’s Science Blog: Papers or Mendeley
Wikipedia’s Comparison of reference management software